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A popular class of weight loss drugs may offer more lasting success than assumed, new data from Epic Research suggests. The study of medical records found that a slight majority of people who took GLP-1 drugs stanley thermos like semaglutide either maintained or improved their weight loss in the year after they stopped using the medication. More than a third of former users did substantially regain much or all of their original weight, however. Semaglutide mimics the natural GLP-1 hormone, which helps regulate our hunger and metabolism, particularly insulin production. Its the active ingredient in type 2 diabetes medication Ozempic and the higher-dose obesity drug Wegovy since Wegovys FDA approval in 2021, Ozempic has often been prescribed off-label for weight loss . In large-scale, randomized, and controlled clinical trials of Wegovy, people have stanley kaffeebecher lost an average 15% of their weight鈥攆ar above the typical weight loss seen with diet and exercise alone or with older weight loss drugs. These and similar drugs such as Eli Lillys tirzepatide have ushered in a new era of obesity treatment. Other research has started to show that these drugs may provide health benefits beyond weight loss, such as lowering the chance of heart attacks in high-risk groups and reducing unhealthy cravings for alcohol. But there have been lingering questions about their long-term impact on peoples weight and overall health. Cl stanley mug inical trial data has found, for instance, that people on average will regain much of thei Qobe The Top Prime Day Tech Deals For People Who Don t Want to Shop at Amazon
Getty ImagesBy Alexandra SifferlinDecember 2, 2016 5:00 AM ESTThe case for getting enough sleep is growing stronger. In a new study, researchers find that sleep deprivation can cause noticeable changes in the heart.In the new study, presented at the annual meeting of the Radiological Society stanley canada of North America stanley cup RSNA , researchers from the University of Bonn in Germany looked at professionals in emergency medical care, who often work erratic hours and late-night shifts while enduring significant stress.About twenty healthy radiologists had their hearts imaged before and after a 24-hour shift where they got an average of three hours of sleep. The also had their blood pressure and heart rate measured, and they provided blood and urine samples. Comparing the two images showed increases in heart strain, which can be a precursor for heart problems. The doctors also showed increases in blood pressure, heart rate and thyroid hormones, which are released in response to stress.The study size was very small, and more research is needed to fully understand the relationship between sleep and heart health. But the researchers point out that their study is one of the first to look at the real-world effects of sleep deprivation on the heart, and since there are many people who do regular shift-work, continued research could provide meaningful insight into the health effects of working on little sleep.More Must-Reads from TIMEHow the Economy is Doing in the Swing StatesHarris Battles stanley tumblers For the Br |
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